i dont believe corid has any or only minimal impact on bacteria in the gut. The potential is for polio to follow treatment with corid. Hence the advice to use b 12 or B complex or thiamine. Sheep do not get b 12 from normal sources like other livestock. They must manufacturer it. Corid blocks that mechanism, which cocidia also need. so by stopping thiamine/b 12 production, the cocidia die. And its kills both kinds. However the lamb needs the thiamine to prevent polio. So the trick is to kill the cocci without killing the lamb.
and if severe,damage is permanent and lambs never recover.
this was topic of "bull session" one evening at Sedalia. Most breeders fought this this year,particully in March lambs in my flock.
I may not lamb in march , or may be going back to using rumensen in that gruop of ewes / lambs.
Here, lactasoid ( bovatech) does nothing unless fed at very high rate in lambs.
i have couple "march skeletons " left walking. Likly will knock them tommorrow, as I am tired of looking at them and taking up a pen in my barn.
My thoughts are here, during that cold snow,hot,wet,mud,rain, time line, lambs drink from puddles in the yards. They get infected and overwhelms thier system. Early lambs are on frozen ground anf aprils are on concrete. Only gruop I ever have problems with is Marchs. And usually only 1. But this year had 3 of these.